INTERPLAY OF FILAGGRIN LOSS-OF-FUNCTION VARIANTS, ALLERGIC SENSITIZATION, AND ECZEMA IN A LONGITUDINAL STUDY COVERING INFANCY TO 18 YEARS OF AGE.

Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.

Immune specific genes as well as genes regulating the formation of skin barrier are major determinants for eczema manifestation.There is a debate as to whether allergic sensitization and filaggrin gene MALE ENERGY (FLG) variants lead to eczema or FLG variants and eczema increase the risk of allergic sensitization.To investigate the time-order betwe

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GEN-RWD Sandbox: bridging the gap between hospital data privacy and external research insights with distributed analytics

Abstract Background Artificial intelligence (AI) has become a pivotal tool in advancing contemporary personalised medicine, with the goal of tailoring treatments to individual patient conditions.This has heightened the demand for access to diverse data from clinical practice and daily life for research, posing challenges due to the sensitive nature

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